Schizophrenia has different clinical manifestations, although, it is one disorder patients divided to two groups type 1 and type 2 .type 1 who have positive and type 2 who have negative signs. They have chronic schizophrenia and treated at least with one antipsychotic drug. With checklist the signs were controlled. In these chronic patients, hallucinations (positive sign) are seen with almost all of negative signs. In the other hand, (1) Flat affect (2) A logia & volition (3) Social inattentiveness (4) Inability to feel intimacy are seen more than another signs. For these patients new antipsychotic must be examined.